| 摘要 |
Antiviral activity is exhibited by compounds having the formula (See formula I) and its pharmaceutically acceptable salts wherein R1 is (See formula II) ( See formula III) (SEE formula IV) (See formula V) (See formula VI) (See formula VII) (See formula VIII) (See formula IX) (See formula X) (See formula XI) (See formula XII) (See formula XIII) (See formula XIV) (See formula XV) (See formula XVI) (See formula XVII) wherein R2 is hydrogen, methyl, fluoro, chloro, bromo, iodo, hydroxy or amino; R3 is fluoro, chloro, bromo, iodo, hydrogen, methyl, trifluoro-methyl, ethyl, n-propyl, 2-fluoroethyl, 2-chloro-ethyl, or trans wherein R4 is chloro, bromo, iodo, hydrogen methyl or trifluoromethyl; R5 is alkyl; R6 is hydrogen, alkyl, substituted alkyl, or aryl; and R7 and R8 are independently hydrogen, -PO3H2 or
|
