摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing L-lysine by a fermentation process using a vitamin B12 non-demanding thermophilic bacterium belonging to the genus Bacillus. SOLUTION: A methanol-assimilating thermophilic bacterium belonging to the genus Bacillus, capable of producing L-lysine, not demanding B12, to be concrete, Bacillus methanolicus having L-lysine analog resistance, is cultured in a medium. L-Lysine is formed and accumulated in a culture product and L-lysine is collected from the culture product to give L-lysine.
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