NATURAL ASPAOLIGONIN TO BE ISOLATED FROM ASARAGUS OKIGOCLONOS MAXIM. AND ISOLATING METHOD THEREOF

摘要

PURPOSE: Provided is a natural aspaoligonin isolated from Asaragus oligoclonos Maxim. Also, an isolating method thereof is provided. The aspaoligonin is potentially developed into medical supplies if its medicinal action is examined. CONSTITUTION: The aspaoligonin represented by formula (1) is isolated from Asaragus oligoclonos Maxim. by the following steps of: grinding the dried roots of Asaragus oligoclonos Maxim.; extracting the grinded roots with methanol at room temperature; filtering the extract solution and concentrating the filtrate under vacuum condition; dissolving the concentrates in distilled water and defatting the solution with ether; extracting the water layer of the defatted solution with butanol to obtain the butanol fragment; purifying the butanol fragment by chromatography on silica gel to obtain 20 fragments; and purifying the 5th fragment by using Sep-Pak C18 to obtain aspaoligonin.