CLONING, EXPRESSION AND CHARACTERISATION OF A CDNA CODING FOR A RAT BRAIN GAMMA-HYDROXYBUTYRATE (GHB) RECEPTOR

摘要

The invention concerns a novel gamma-hydroxybutyrate (GHB) receptor polypeptide characterised by it functional activities, the cloning of the cDNA coding for said receptor, vectors and transformed cells, methods for selecting compounds useful as medicine for preventing and/or treating pathologies associated directly or indirectly with the activity of said receptor or its natural ligand, GHB.