This invention describes a nucleic acid delivery vehicle construct for transfecting and/or infecting a target cell. The construct is made of a delivery vehicle and a bifunctional complex for linking the delivery vehicle to a target cell. The bifunctional complex has a delivery vehicle binding molecule or fragment ("delivery vehicle binding portion"), a molecule or fragment thereof that binds to a cell surface molecule on the target cell ("cell surface molecule binding portion") and a linker which connects the molecules or fragments.
申请公布号
WO9940214(A8)
申请公布日期
2001.03.01
申请号
WO1999US02680
申请日期
1999.02.08
申请人
GENZYME CORPORATION;O'RIORDAN, CATHERINE;ROMANCZUK, HELEN;WADSWORTH, SAMUEL, C.
发明人
O'RIORDAN, CATHERINE;ROMANCZUK, HELEN;WADSWORTH, SAMUEL, C.