发明名称 NUCLEIC ACID DELIVERY VEHICLES
摘要 This invention describes a nucleic acid delivery vehicle construct for transfecting and/or infecting a target cell. The construct is made of a delivery vehicle and a bifunctional complex for linking the delivery vehicle to a target cell. The bifunctional complex has a delivery vehicle binding molecule or fragment ("delivery vehicle binding portion"), a molecule or fragment thereof that binds to a cell surface molecule on the target cell ("cell surface molecule binding portion") and a linker which connects the molecules or fragments.
申请公布号 WO9940214(A8) 申请公布日期 2001.03.01
申请号 WO1999US02680 申请日期 1999.02.08
申请人 GENZYME CORPORATION;O'RIORDAN, CATHERINE;ROMANCZUK, HELEN;WADSWORTH, SAMUEL, C. 发明人 O'RIORDAN, CATHERINE;ROMANCZUK, HELEN;WADSWORTH, SAMUEL, C.
分类号 A61K47/48;A61K48/00;C07K14/00;C07K16/08;C07K16/28;C07K16/30;C12N15/861;C12N15/864;C12N15/87;(IPC1-7):C12N15/86 主分类号 A61K47/48
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