NEW EFFECTORS OF DIPEPTIDYL PEPTIDASE IV FOR TOPICAL USE

摘要

The invention relates to compounds of general formula (I), wherein A represents an amino acid with at least one functional group in the side chai n; while B is a chemical compound covalently bound to a functional group of the side chain of A, namely oligopeptide with a chain length of up to 20 amino acids with the exception of glycine homopolymers which have up to 6 glycine monomers or polyethylene glycols with molar masses of up to 20000 g/mole; C represents a thiazolidine, pyrrolidine, cyanopyrrolidine, hydroxyproline, dehydroproline or piperidine group which is amide bonded. These compounds ca n be used to topically influence the activity of dipeptidyl Peptidase IV.