| 发明名称 |
FARNESYL-PROTEIN TRANSFERASE INHIBITORS |
| 摘要 |
Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described.
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| 申请公布号 |
WO9943314(A9) |
申请公布日期 |
2001.03.01 |
| 申请号 |
WO1999US04124 |
申请日期 |
1999.02.25 |
| 申请人 |
INTERNATIONAL PHYTOCHEMISTRY RESEARCH LABS, LTD. |
发明人 |
SHAIKENOV, TATTYM, E.;ADEKENOV, SERGAZY, M. |
| 分类号 |
C07D307/93;A61K31/28;A61K31/34;A61K31/343;A61K31/35;A61K31/365;A61K31/475;A61K31/505;A61K31/5377;A61K31/56;A61K31/66;A61K31/661;A61K31/6615;A61K31/675;A61K31/70;A61K33/24;A61K45/06;A61P35/00;A61P43/00;C07D303/38;C07D307/935;C07D493/04;C07D493/10;C07D493/14;C07D493/20;C07F9/09;C07F9/117;C07F9/655;(IPC1-7):A61K31/34;C07C53/136;C07D407/02 |
主分类号 |
C07D307/93 |
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