发明名称 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF
摘要 The present invention relates to ester derivatives of 1,4-dihydropyridine-5-carboxylic acid of formula (I) wherein R1, R2 and R3 may be a coumarin group. These compounds possess an anti-viral activity. Most of the anti-viral compounds known in the art are nucleoside-derivatives. Various viruses become resistent against these. Because the compounds according to the invention are not nucleoside-derivatives, they form a suitable alternative. The invention also relates to a method of preparing the anti-viral substances according to the invention.
申请公布号 WO0114370(A1) 申请公布日期 2001.03.01
申请号 WO2000NL00582 申请日期 2000.08.23
申请人 REPHARTOX;STERK, GEERT, JAN;VAN DER WERF, JAN, FETZE 发明人 STERK, GEERT, JAN;VAN DER WERF, JAN, FETZE
分类号 C07D405/12;(IPC1-7):C07D405/12;A61K31/44 主分类号 C07D405/12
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