| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: present invention refers to the chemical pharmaceutical industry and relates to the composition, method of obtaining and application of the means based on the perfluorinated emulsions intended for usage as blood substitutes and other medicinal preparations. The essence of the method lies in the development of the method and composition consisting of two promptly excreting (C8-C10) and/or slowly excreting (C11-C12) perfluorcarbons in the ratio from 1/1 to 10/10, or mixture of three perfluorocarbons: two promptly excreting (C8-C10) and one slowly excreting (C11-C12), or one promptly excreting (C8-C10) and two slowly excreting (C11-C12) in the ratio 1/1/1 to 10/10/10, or mixture of four perfluorocarbons: two promptly excreting (C8-C10) and two slowly excreting (C11-C12) in the ratio 1/1/1/1 to 10/10/10/10. The perfluorocarbon mixture has the concentration in the range from 1% (0.5% vol.) to 100% (50% vol.) with average particle size in the range 30-80 nm, it is emulgated with proxanol-268 taken in amount from 0.2% to 20% with molecular mass 6000-12000. ^ EFFECT: compound contains acceptable electrolyte solution or other acceptable media. ^ 17 cl, 12 ex, 1 tbl, 1 dwg |
