| 发明名称 |
PIPERIDINE ALCOHOLS |
| 摘要 |
The invention relates to compounds of formula (I), wherein R1, R2 and A have the meanings given in claim 1, are potent 5-HT2A antagonists and are suitabl e for treating psychoses, schizophrenia, depression, neurological disorders, impaired memory, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease, eating disorders such as bulimia and anorexia nervosa, Pre-Menstrual Syndrome and/or for positively influenci ng obsessive-compulsive disorders, (OCD). |
| 申请公布号 |
CA2382295(A1) |
申请公布日期 |
2001.03.01 |
| 申请号 |
CA20002382295 |
申请日期 |
2000.08.08 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
BARTOSZYK, GERD;ACKERMANN, KARL-AUGUST;HARTING, JURGEN;VAN AMSTERDAM, CHRISTOPH;PRUCHER, HELMUT;BOTTCHER, HENNING;SEYFRIED, CHRISTOPH;GREINER, HARTMUT;GOTTSCHLICH, RUDOLF |
| 分类号 |
A61K31/445;A61K31/4523;A61K31/538;A61P5/24;A61P15/00;A61P25/00;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P43/00;C07D211/18;C07D211/22;C07D401/06;C07D405/06;C07D409/06;C07D413/06;C07D417/06 |
主分类号 |
A61K31/445 |
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