| 发明名称 |
PLEUROMUTILIN beta -KETOESTERS |
| 摘要 |
Pleuromultilin beta -ketoesters of Formula (IA) or (IB), in which R<1> is a nitrogen containing heterocycle, an optionally substituted aryl or optionally substituted heteroaryl group, or CH2R<5>; R<2> is vinyl or ethyl; R<3> is H, OH or F; and R<4> is H; or R<3> is H and R<4> is F; in which R<5> is halogen or SR<6>; and R<6> is aminoalkyl, a nitrogen containing heterocycle, or an optionally substituted aryl or optionally substituted heteroaryl groupare of use in therapy as antibacterial agents.
|
| 申请公布号 |
WO0114310(A1) |
申请公布日期 |
2001.03.01 |
| 申请号 |
WO2000EP07687 |
申请日期 |
2000.08.04 |
| 申请人 |
SMITHKLINE BEECHAM P.L.C.;DEAN, DAVID, KENNETH;NAYLOR, ANTOINETTE;TAKLE, ANDREW, KENNETH |
发明人 |
DEAN, DAVID, KENNETH;NAYLOR, ANTOINETTE;TAKLE, ANDREW, KENNETH |
| 分类号 |
C07C69/00;C07C323/52;C07D211/34;C07D213/55;C07D239/26;C07D239/38;C07D249/14;C07D277/64;C07D277/76;C07D285/12;C07D285/135;C07D453/02;(IPC1-7):C07C69/738;C07C69/716;C07D487/08;A61K31/215;A61K31/45;A61K31/441;A61K31/513 |
主分类号 |
C07C69/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
