AMINOHYDROXYLATION OF OLEFINS

摘要

Osmium-catalyzed aminohydroxylation reactions are accelerated and expanded in scope by the use of olefinic substrates having ionic groups, either anionic or cationic. The use of ionic groups on olefinic substrates also extends the aminohydroxylatable positions of unsaturations to include alpha , beta , beta , gamma , and gamma , delta positions, with respect to such ionic groups. A mechanism for the disclosed acceleration and extension is provided.