发明名称 |
GROUP A STREPTOCOCCAL POLYSACCHARIDE IMMUNOGENIC COMPOSITIONS AND METHODS |
摘要 |
<p>This invention provides a novel immunogenic composition and vaccine, processes for producing them and methods for immunization against infections and disease caused by group A Streptococci. The compositions include group A streptococcal polysaccharide covalently linked to protein or liposomes to form immunogenic conjugates. The method of immunization for this invention comprises administering to an individual an immunogenic amount of group A polysaccharide. The group A polysaccharide may be administered as a vaccine either on its own, conjugated to proteins or conjugated to liposomes. Additionally, the group A polysaccharides may be associated with an adjuvant. This invention is particularly useful for providing both active and passive immunogenic protection for those populations most at risk of contracting group A Streptococcal infections and disease namely adults, pregnant women and in particular infants and children.</p> |
申请公布号 |
GR3034916(T3) |
申请公布日期 |
2001.02.28 |
申请号 |
GR20000402622T |
申请日期 |
2000.11.27 |
申请人 |
THE ROCKEFELLER UNIVERSITY;NORTH AMERICAN VACCINE, INC. |
发明人 |
BLAKE, MILAN, S.;ZABRISKIE, JOHN, B.;TAI, JOSEPH, Y.;MICHON, FRANCIS |
分类号 |
A61K9/127;A61K39/09;A61K39/385;A61P31/04;(IPC1-7):A61K39/09 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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