Influenza vaccine

摘要

The present invention is concerned with an Influenza surface antigen vaccine obtainable by production from Influenza Viruses propagated on animal cell culture and having a host cell DNA content equal to or less than 25 pg per dose. The present invention is also concerned with a method for the preparation of surface antigen proteins from Influenza Viruses propagated on an animal cell culture comprising the subsequent steps of: a. treatment of the whole virus containing fluid obtained from the cell culture with a DNA digesting enzyme, and b. adding a cationic detergent, followed by isolation of the surface antigen proteins.