发明名称 Pyrazolopyrimidine and pyrazolines and process for preparation thereof
摘要 The present invention is concerned with pyrazolopyrimidines and pyrazolotriazines of the general formulaand their pharmaceutically acceptable salts.Surprisingly, these compounds evidence selective affinity to 5HT-6 receptors. They are accordingly suitable for use in the treatment and prevention of central nervous disorders such as, for example, psychoses, schizophrenia, manic depressions, depressions, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
申请公布号 US6194410(B1) 申请公布日期 2001.02.27
申请号 US19990256927 申请日期 1999.02.24
申请人 HOFFMAN-LA ROCHE INC. 发明人 BOES MICHAEL;RIEMER CLAUS;STADLER HEINZ
分类号 A61K31/00;A61K31/4162;A61K31/505;A61K31/519;A61K31/529;A61K31/53;A61K31/535;A61K31/5375;A61K31/5377;A61P9/10;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P43/00;C07D231/54;C07D251/72;C07D487/04;C07D495/14;(IPC1-7):A01N43/64;C07D251/00;C07D487/00 主分类号 A61K31/00
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