发明名称 |
Apt-sensitive potassium channel gene-defective animals |
摘要 |
A Kir6.2 gene-defective, non-human mammal, a mouse in particular, its tissues and cells are provided, wherein the ATP-sensitive potassium channel Kir6.2 gene, one of the subunits of KATP channels essential for insulin secretion by pancreatic beta-cells, is lost from one or both of the allelic loci.
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申请公布号 |
US6194634(B1) |
申请公布日期 |
2001.02.27 |
申请号 |
US19980213864 |
申请日期 |
1998.12.17 |
申请人 |
JCR PHARMACEUTICALS CO., LTD.;SUSUMU SEINO |
发明人 |
SEINO SUSUMU;MIKI TAKASHI;MIYAZAKI JUNICHI |
分类号 |
A01K67/027;A01K67/00;C07K14/705;C12N5/10;C12N15/09;C12N15/85;(IPC1-7):A01K67/027 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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