发明名称 NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS
摘要 There is provided compounds of formula (I), wherein R 1, R x, Y, R y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
申请公布号 KR20010013982(A) 申请公布日期 2001.02.26
申请号 KR19997012009 申请日期 1998.06.09
申请人 ASTRAZENECA AB 发明人 KARLSSON OLLE;LINSCHOTEN MARCEL;NYSTROEM JAN-ERIK
分类号 A61K;A61K31/397;A61K31/40;A61K31/401;A61P7/02;A61P43/00;C07D;C07D205/04;C07D207/16;C07D405/06;(IPC1-7):G06F17/60 主分类号 A61K
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