| 摘要 |
The invention relates to a method for indirectly determining the blood- clotting status. The inventive method comprises the following steps: a) collecting body fluids which contain a protein that can be modified by a vitamin K-dependent .gamma.-carboxylase, b) determining at least two concentrations selected from a group consisting of a first concentration (C1 ) of carboxylated protein, a second concentration (C2) of decarboxylated prote in and an entire concentration (C3) of carboxylated and decarboxylated protein, whereby the first concentration (C1) is determined using a first antibody (A1), the second concentration using a second antibody (A2) and the third concentration (C3) using a third antibody (A3), c) generating a first quotie nt (Q1) from the first (C1) and second concentration (C2) or generating a secon d quotient (Q2) from the third (C3) and first concentration (C1) or generating a third quotient (Q3) from the third (C3) and second concentration (C2), where by a concentration (C1, C2, C3) which has not been determined in step b) and which is required for generating the first (Q1), the second (Q2) or the thir d quotient (Q3) is calculated according to the following relation: C3 - C2 = C 1 and d) the first, second or third quotient (Q1, Q2, Q3) are correlated with the blood-clotting status.
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