1-TRIFLUOROMETHYL-4-HYDROXY-7-PIPERIDINYL-AMINOMETHYLCHROMAN DERIVATIVES

摘要

This invention relates to novel 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives of formula (I) wherein R<1> is C1-C6 alkyl; R<2> is hydrogen, C1-C6 alkyl, halo C1-C6 alkyl or phenyl; R<3> is hydrogen or halo; and R<4> and R<5> are independently hydrogen, C1-C6 alkyl or halo C1-C6 alkyl, their pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and the use of such compounds to treat CNS, gastrointestinal and other disorders.