| 摘要 |
<p>The invention relates to a method for indirectly determining the blood-clotting status. The inventive method comprises the following steps: a) collecting body fluids which contain a protein that can be modified by a vitamin K-dependent η-carboxylase, b) determining at least two concentrations selected from a group consisting of a first concentration (C1) of carboxylated protein, a second concentration (C2) of decarboxylated protein and an entire concentration (C3) of carboxylated and decarboxylated protein, whereby the first concentration (C1) is determined using a first antibody (A1), the second concentration using a second antibody (A2) and the third concentration (C3) using a third antibody (A3), c) generating a first quotient (Q1) from the first (C1) and second concentration (C2) or generating a second quotient (Q2) from the third (C3) and first concentration (C1) or generating a third quotient (Q3) from the third (C3) and second concentration (C2), whereby a concentration (C1, C2, C3) which has not been determined in step b) and which is required for generating the first (Q1), the second (Q2) or the third quotient (Q3) is calculated according to the following relation: C3 - C2 = C1 and d) the first, second or third quotient (Q1, Q2, Q3) are correlated with the blood-clotting status.</p> |
