PNEUMOCOCCAL VACCINES

摘要

The invention relates to the use of a protein or a fragment thereof of S. pneumoniae, its use for the preparation of a vaccine for the preventive treatment of a S. pneumoniae infection, compositions comprising protease maturation protein of S. pneumoniae infection, or a fragment thereof, vaccines comprising said protein or fragment thereof, use of a nucleic acid sequence encoding for said protein or fragment thereof, vectors wherein the nucleic acid sequence is brought to expression and to recombinant protease maturation protein or a fragment thereof or (functional) homologues thereof and to a method for the determination of proteins with opsonophagocytic activity and/or in vivo immunisation and/or in vivo immune protection.