| 发明名称 |
Parvovirus NS1 variants |
| 摘要 |
<p>The present invention relates to a parvovirus NS1 variant having a shifted equilibrium between the DNA replication and transcription activities (a) and the cytotoxicity activity (b). Furthermore, this invention relates to DNAs coding for these parvovirus NS1 variants and methods of producing them. Additionally, this invention concerns antibodies directed against the parvovirus NS1 variants as well as the use of the DNAs and the parvovirus NS1 variants.</p> |
| 申请公布号 |
EP1077260(A1) |
申请公布日期 |
2001.02.21 |
| 申请号 |
EP19990115161 |
申请日期 |
1999.08.13 |
| 申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM<BR>STIFTUNG DES OEFFENTLICHEN RECHTS |
发明人 |
NUEESCH, JUERG, DR.;ROMMELAERE, JEAN, PROF. DR. |
| 分类号 |
A61K38/00;C07K14/015;C12N15/35;(IPC1-7):C12N15/35;C07K16/08;G01N33/569;C12Q1/70;A61K35/76;A61K48/00 |
主分类号 |
A61K38/00 |
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