PORE-FORMING PROTEIN CONJUGATE COMPOSITIONS AND METHODS

摘要

The present disclosure relates to compositions and methods based on a fast, efficient chemical reaction for conjugating a pore- forming protein, such as α-hemolysin, to a biomolecule, such as antibodies, receptors, and enzymes, such as DNA polymerase, and the use of such pore-forming protein conjugates in nanopore devices and methods.