| 发明名称 |
Human leukocyte 12-lipoxygenase and its role in the pathogenesis of disease states |
| 摘要 |
The present invention relates to a method for inhibiting the etiology of disease in patients having a disease state caused by an excess of 12-lipoxygenase or its products. In particular, the invention provides for administration of a human leukocyte 12-lipoxygenase pathway inhibitor to inhibit disease etiology, to inhibit the proliferation of breast cancer and to increase insulin receptor phosphorylation in a patient having Type II diabetics.
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| 申请公布号 |
US6191169(B1) |
申请公布日期 |
2001.02.20 |
| 申请号 |
US19970945744 |
申请日期 |
1997.11.03 |
| 申请人 |
CITY OF HOPE |
发明人 |
NADLER JERRY L.;NATARAJAN RAMA |
| 分类号 |
A61K31/00;A61K31/045;A61K31/05;A61K31/155;A61K31/195;A61K31/20;A61K31/35;A61K31/352;A61K31/44;A61K31/4439;A61K31/575;A61K38/00;A61K38/08;A61K38/18;A61K38/20;A61K38/43;C12N9/02;C12N15/113;C12Q1/26;G01N33/573;G01N33/68;(IPC1-7):A61K31/195 |
主分类号 |
A61K31/00 |
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