<p>The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and i n vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.</p>
申请公布号
CA2379909(A1)
申请公布日期
2001.02.15
申请号
CA20002379909
申请日期
2000.08.04
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
SMITH, GEORGE M.;HU, ZHIBING;ALIKACEM, NADIR;NELSON, KEVIN D.;RADULESCU, DELIA;ROMERO-SANCHEZ, ANDRES A. A.;WAGGONER, PAULA
