发明名称 |
SINGLE-CHAIN POLYPEPTIDES COMPRISING TROPONIN I N-TERMINAL FRAGMENTS AND TROPONIN C |
摘要 |
This invention relates to single-chain polypeptides and their genetic sequences comprising a human cardiac troponin I N-terminal fragment and troponin C. The N-terminal fragment may or may not have the intact N-terminus. The single-chain polypeptide may be expressed recombinantly, and a linker or spacer polypeptide or peptide may be interposed between the troponin sequences. The single-chain polypeptides have utility as controls or calibrators for troponin assays, for the purification of troponin subunits and as an antigen for the preparation of antibodies.
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申请公布号 |
WO0111043(A1) |
申请公布日期 |
2001.02.15 |
申请号 |
WO2000IB01105 |
申请日期 |
2000.08.07 |
申请人 |
SPECTRAL DIAGNOSITCS, INC.;SHI, QINWEI;LIU, SHIGUI;LING, MINGFU |
发明人 |
SHI, QINWEI;LIU, SHIGUI;LING, MINGFU |
分类号 |
A61K38/00;C07K14/47;C12N1/21;C12N15/12;G01N33/68;(IPC1-7):C12N15/12;C12N15/62 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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