摘要 |
Selected compounds of formula (I) are antibacterial agents: formula (I) wherein R2 represents a substituted or unsubstituted C1-C6 alkyl, cycloalkyl (C1-C6 alkyl)- or aryl (C1-C6 alkyl)- group, and A represents a group of formula (IA), or (IB) wherein R4 represents the side chain of a natural or non-natural alpha amino acid, and R5 and R6 are each independently hydrogen or C1-C6 alkyl, heterocyclic or aryl (C1-C6 alkyl)-, R5 and R6 when taken together with the nitrogen atom to which they are attached from an optionally substituted saturated heterocyclic ring of 3 to 8 atoms which ring is optionally fused to a carbocyclic or second heterocyclic ring.
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申请人 |
BRITISH BIOTECH PHARMACEUTICALS LIMITED;HUNTER, MICHAEL, GEORGE;BECKETT, RAYMOND, PAUL;CLEMENTS, JOHN, MARTIN;WHITTAKER, MARK;DAVIES, STEPHEN, JOHN;PRATT, LISA, MARIE;SPAVOLD, ZOE, MARIE;LAUNCHBURY, STEVEN |
发明人 |
HUNTER, MICHAEL, GEORGE;BECKETT, RAYMOND, PAUL;CLEMENTS, JOHN, MARTIN;WHITTAKER, MARK;DAVIES, STEPHEN, JOHN;PRATT, LISA, MARIE;SPAVOLD, ZOE, MARIE;LAUNCHBURY, STEVEN |