Kit for diagnosis of tubercle bacilli

摘要

By using a kit for diagnosis of tubercle bacilli containing a substrate, on which immobilized through a covalent bond is an oligonucleotide which is derived from a gene on tubercle bacilli genome that is responsible for drug resistance for one or more drugs employed in tuberculosis treatment and synthesized based on nucleotide sequences obtained from a wild-type tubercle bacilli susceptible to the drug or drugs and a mutant type tubercle bacilli resistant to at least one of the drugs, differentiation of drug resistance of tubercle bacilli or determination of infection with tubercle bacilli is performed by hybridization of the oligonucleotide with a nucleic acid derived from a microorganism to be tested.