| 发明名称 |
Transgenic mouse having a disrupted amyloid precursor protein gene |
| 摘要 |
The present invention relates to a transgenic nonhuman animal lacking native amyloid precursor protein. The transgenic mouse of the invention may be used in the study of Alzheimer's Disease and disorders involving the central nervous system.
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| 申请公布号 |
US6187992(B1) |
申请公布日期 |
2001.02.13 |
| 申请号 |
US19990266475 |
申请日期 |
1999.03.11 |
| 申请人 |
MERCK & CO., INC.;MERCK FROSST CANADA & CO. |
发明人 |
ZHENG HUI;CHEN HOWARD Y.;TRUMBAUER MYRNA E.;VAN DER PLOEG LEONARDUS H. T.;SEABROOK GUY;SIRINATHSINGHJI DALIP |
| 分类号 |
C12N15/85;(IPC1-7):A01K67/00;A01K67/027;G01N33/00;C12N15/00;C12N5/08 |
主分类号 |
C12N15/85 |
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