发明名称 Bis(9-aminoacridine) DNA intercalating agents having antitumor activity
摘要 A series of bis-acridinyl DNA intercalating agents with anticancer cell activity represented by formula (I), where Z is a linear arrangement of multiple aromatic rings, containing at least three aromatic rings, or at least two alicyclic rings, said rings being linked in a 1,4 or 1,3 manner are provided. Methods of inhibiting cancer cells and treating patients having cancer with these agents are also provided.
申请公布号 US6187787(B1) 申请公布日期 2001.02.13
申请号 US20000446171 申请日期 2000.02.15
申请人 TRUSTEES OF DARTMOUTH COLLEGE 发明人 GRIBBLE GORDON W.;JAYCOX GARY D.;MOSHER MICHAEL
分类号 A61P35/02;C07D219/12;(IPC1-7):A61K31/473;C07D401/08;C07D401/10;C07D401/12 主分类号 A61P35/02
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