| 发明名称 |
Methods for the identification of patients at risk for heart failure |
| 摘要 |
A method of predicting the clinical outcome of patients suffering from congestive heart failure by identifying patients with a mutant allele of the AMPD1 gene is provided. Methods for increasing survival time in patients suffering from congestive heart failure by administering compositions which inhibit AMPD1 activity are also provided.
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| 申请公布号 |
US6187542(B1) |
申请公布日期 |
2001.02.13 |
| 申请号 |
US19990269807 |
申请日期 |
1999.11.24 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
HOLMES EDWARD;LOH EVAN;SWAIN JUDITH |
| 分类号 |
C12N15/09;A61K45/00;A61P9/04;C12N9/78;C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04 |
主分类号 |
C12N15/09 |
| 代理机构 |
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