发明名称 |
Subtilisin protease variants having amino acid substitutions in defined epitope regions |
摘要 |
The present invention relates to variants of subtilisin-like proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates to variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a substitution of one or more epitope regions. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants. |
申请公布号 |
AU6085800(A) |
申请公布日期 |
2001.02.13 |
申请号 |
AU20000060858 |
申请日期 |
2000.07.11 |
申请人 |
THE PROCTER AND GAMBLE COMPANY |
发明人 |
ELIZABETH ELLEN SIKORSKI;DONN NELTON RUBINGH |
分类号 |
A61K8/00;A61K8/66;A61K8/96;A61Q1/02;A61Q1/14;A61Q19/00;A61Q19/10;C11D3/386;C12N9/54;C12N15/57 |
主分类号 |
A61K8/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|