PRODUCTION OF AROMATIC DICARBOXYLIC ACID DIAMIDE

摘要

PROBLEM TO BE SOLVED: To industrially advantageously obtain the subject compound in a high yield hardly causing a by-product of carboxylic acid by amidating an aromatic dinitrile in the presence of an inorganic strong base in water-containing dimethyl sulfoxide. SOLUTION: An aromatic dinitrile (e.g. benzenedinitrile, etc.), is amidated in the presence of an inorganic strong base (preferably sodium hydroxide) in water-containing dimethyl sulfoxide to give the objective compound. The amount of the inorganic strong base used is preferably 0.01-1 mol based on 1 mol of the aromatic dinitrile. The amount of water used is preferably 1.5-50 mols based on 1 mol of nitrile group. The amount of dimethyl sulfoxide is preferably an amount to make the preparation concentration of the aromatic dinitrile 1-50 wt.%. Preferably the reaction temperature of the amidation is 50-150 deg.C and the reaction time is 0.5-10 hours.