摘要 |
Prevention or therapy of inflammatory diseases caused by invasion of leukocytes such as monocytes, lymphocytes and eosinophils, by providing a substance which inhibits cell adhesion via an adhesion molecule, especially adhesion molecule VLA-4, is disclosed. A group of carboxylic acid derivatives represented by, for example, <CHEM> and adhesion molecule inhibitors comprising the same as an effective ingredient were provided. <IMAGE> |