发明名称 N-(indolcarbonyl-)piperazin derivatives
摘要 The invention relates to compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>4 </SUP>and R<SUP>5 </SUP>have the meaning given in Claim 1. Said compounds are potent 5-HT<SUB>2A</SUB>-antagonists and are suitable for the treatment of psychosis, schizophrenia, depression, neurological disorders, memory disorders. Parkinson's disease, amyntrophic lateral schlerosis, Alzheimer's disease, Huntington's disease, eating disorders, e.g. nervous bulimia and anorexia and premenstrual syndrome and/or for positively influencing compulsive behaviours (obsessive-compulsive disorder, OCD).
申请公布号 AU6270400(A) 申请公布日期 2001.02.13
申请号 AU20000062704 申请日期 2000.07.07
申请人 MERCK PATENT G.M.B.H 发明人 DR. HENNING BOTTCHER;HARTMUT GREINER;JURGEN HARTING;GERD BARTOSZYK;CHRISTOPH SEYFRIED;CHRISTOPH VAN AMSTERDAM
分类号 C07D403/06;A61K31/496;A61P3/04;A61P21/02;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;C07D209/04;C07D209/08;C07D209/12;C07D209/38;C07D209/40;C07D209/42;C07D209/82;C07D295/04;C07D409/12 主分类号 C07D403/06
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