GEOMETRICAL ISOMER OF ACRYLONITRILE COMPOUND, MIXTURE THEREOF, AND PROCESS FOR PRODUCING THESE

摘要

A geometrical isomer of an acrylonitrile compound represented by formula (I) or of a salt of the compound; or a mixture of the isomer [wherein T is phenyl or pyridyl each substituted by R2; Q is phenyl, thienyl, pyridyl, or benzyl each optionally substituted by R3; R1 is -C(=O)R4 or -C(=S)R4; and R4 is optionally substituted alkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio, cycloalkyl, cycloalkyloxy, cycloalkylthio, -N(R5)R6, phenyl, phenoxy, phenylthio, benzyl, benzyloxy, benzylthio, -J, -O-J, or -S-J]. The geometrical isomer has a longer retention time when analyzed by reversed-phase liquid chromatography in which a packing comprising silica having chemically bonded thereto an alkyl selected among trimethyl, octyl, and octadecyl is used as the stationary phase and a polar solvent selected among water, methanol, and acetonitrile is used as the mobile phase. The geometrical-isomer mixture comprises the geometrical isomer in a larger proportion.