摘要 |
<p>Compounds of formula (I) wherein: R is hydrogen; C1-C6 alkyl optionally substituted with one or more primary, secondary or tertiary amino groups, hydroxy or carboxy groups; C5-C6 cycloalkyl; aralkyl; heteroalkyl; aryl; heteroaryl; R1 is hydrogen; C1-C6 alkyl optionally substituted with one or more primary, secondary or tertiary amino groups, hydroxy or carboxy groups; C5-C6 cycloalkyl; aralkyl; heteroalkyl; R2 is hydrogen; C1-C6 alkyl optionally substituted with one or more primary, secondary or tertiary amino groups, hydroxy or carboxy groups; C5-C6 cycloalkyl; aralkyl; aryl; heteroaryl; heteroarylalkyl; C1-C6 acyl; X is one or more groups independently selected from hydrogen, C1-C6 alkyl, hydroxy, C1-C4 alkoxy, C1-C3 haloalkoxy, amino, C1-C3 alkylamino, C1-C3- acylamino, C1-C3 alkylsulfonylamino, halogen, nitro, cyano, carboxy, C1-C3 alkoxycarbonyl, sulfonyl, C1-C3- alkylsulfonyl, aminosulfonyl, C1-C3-alkylaminosulfonyl, trifluoromethyl with antitumor activity.</p> |