发明名称 |
METHOD OF DESIGNING DRUGS THROUGH REVERSE POLYMORPHISM OF TARGET GENES |
摘要 |
<p>This invention relates to a method of determining the most efficacious and safe drug for a population of subjects to modulate a gene or gene product (e.g., protein or polypeptide) by determining the nucleic acid sequence of a ll or a portion of a gene and/or all or a portion of the encoded amino acid sequence of that gene with the lowest frequency of polymorphisms.</p> |
申请公布号 |
CA2379250(A1) |
申请公布日期 |
2001.02.08 |
申请号 |
CA20002379250 |
申请日期 |
2000.07.28 |
申请人 |
GENOME THERAPEUTICS CORPORATION |
发明人 |
LEIGHTON, JEFF;SMITH, DOUGLAS;THOMANN, HANS-ULRICH;KELLY, CHRISTOPHER T. |
分类号 |
C12Q1/68;G06F19/22;G06F19/26;(IPC1-7):C12P19/30 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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