| 发明名称 |
NUCLEIC ACID LIGANDS TO HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR (HGF/SF) OR ITS RECEPTOR C-MET AND TO INTEGRINS |
| 摘要 |
The invention provides nucleic acid ligands to hepatocyte growth factor/scatter factor (HGF) and its receptor c-met. The invention also provides nucleic acid ligands to integrins. The nucleic acid ligands of the instant invention are isolated using the SELEX method. SELEX is an acronym f or Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the invention are useful as diagnostic and therapeutic agents.</S DOAB>
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| 申请公布号 |
CA2381004(A1) |
申请公布日期 |
2001.02.08 |
| 申请号 |
CA20002381004 |
申请日期 |
2000.07.24 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
RABIN, ROSS;JANJIC, NEBOJSA;GOLD, LARRY;LOCHRIE, MICHAEL;STEPHENS, ANDREW;RUCKMAN, JUDY |
| 分类号 |
G01N33/50;A61K31/7088;A61K31/7105;A61K31/711;A61K31/712;A61K38/00;A61P7/02;A61P9/10;A61P15/00;A61P17/06;A61P19/10;A61P27/06;A61P29/00;A61P35/00;C07H21/00;C07H21/02;C07H21/04;C12N15/09;C12P19/34;C12Q1/68;(IPC1-7):C07H21/04;A61K48/00;C12N15/85;C12N15/86 |
主分类号 |
G01N33/50 |
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