发明名称 |
PREVENTING IMMUNE-MEDIATED ABORTION BY INHIBITING COSTIMULATION |
摘要 |
Method of inhibiting and diagnosing spontaneous abortion in a subject are provided. The subject methods are based, inter alia, on the administration of an agent that inhibits a costimulatory signal in a T cell such that spontaneous abortion in the subject is inhibited. The subject methods are also based on the levels of adhesion molecules, inflammatory cytokines, and immune cell surface molecules which are altered in spontaneous abortion. |
申请公布号 |
WO0108700(A1) |
申请公布日期 |
2001.02.08 |
申请号 |
WO2000US20827 |
申请日期 |
2000.07.28 |
申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
LING, VINCENT;GRAY, GARY, S.;KEITH, JAMES, C.;MAGANTI, SRINIVAS |
分类号 |
A61K38/17;C07K14/725;C07K16/28;(IPC1-7):A61K38/18;A61K39/395;C07K14/435;C07K14/475;C07K16/18;C07K16/22;C07K19/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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