This invention relates to an isolated nucleic acid fragment encoding an AMP deaminase or adenosine deaminase, a transformed host cell comprising the nucleic acid fragment, and a transgenic plant comprising the nucleic acid fragment. The invention also relates to the construction of a chimeric gene encoding all or a substantial portion of an AMP or adenosine deaminase, and a chimeric gene comprising the isolated fragment in sense or antisense orientation. This invention further relates to a method for altering expression level of AMP deaminase or adenosine deaminase in a transformed host cell, and a method for evaluating a compound that affects the activity of an AMP deaminase or an adenosine deaminase.
申请公布号
WO0109305(A2)
申请公布日期
2001.02.08
申请号
WO2000US21009
申请日期
2000.07.28
申请人
E.I. DU PONT DE NEMOURS AND COMPANY;PIONEER HI-BRED INTERNATIONAL, INC.;CASPAR, TIMOTHY;FALCO, SAVERIO, CARL;SAKAI, HAJIME;WENG, ZUDE;HU, XU