| 发明名称 |
2,7-Substituted octahydro-1H-pyrido (1,2-A)pyrazine derivatives as ligands for serotonin receptors |
| 摘要 |
<p>Substituted pyrido 1,2-apyrazines of general formula I; wherein Ar and Ar<1> represent various carbocyclic and heterocyclic aromatic rings; A represents O, S, SO, SO2, CHOH, C=O, or -(CR<3>R<4>); and n is 0-2, as well as precursors thereto, are ligands for dopamine receptor subtypes and serotonin (5HT) within the body and are therefore useful in the treatment of disorders of the dopamine and serotonin systems: <CHEM></p> |
| 申请公布号 |
EP1074257(A1) |
申请公布日期 |
2001.02.07 |
| 申请号 |
EP20000306611 |
申请日期 |
2000.08.03 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
DESAI, KISHOR AMRATLAL;FLIRI, ANTON FRANZ JOSEF;SANNER, MARK ALLEN |
| 分类号 |
A61K31/506;C07D471/04;A61K31/495;A61K31/4985;A61P1/04;A61P1/08;A61P9/10;A61P15/00;A61P15/08;A61P25/04;A61P25/06;A61P25/14;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P35/00;A61P43/00;(IPC1-7):A61K31/495;A61K31/505;A61K31/50 |
主分类号 |
A61K31/506 |
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