发明名称 |
Complement-resistant non-mammalian DNA viruses and uses thereof |
摘要 |
Disclosed are methods, nucleic acids, and cells for expressing an exogenous gene in a mammalian cell, involving (i) introducing into the cell a complement-resistant non-mammalian DNA virus (e.g., a baculovirus), optionally having an altered coat protein, the genome of which virus carries an exogenous gene, and (ii) growing the cell under conditions such that the gene is expressed.
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申请公布号 |
US6183993(B1) |
申请公布日期 |
2001.02.06 |
申请号 |
US19990329368 |
申请日期 |
1999.06.10 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;BIOGEN, INC. |
发明人 |
BOYCE FREDERICK M.;BARSOUM JAMES G. |
分类号 |
C12N15/09;A61K31/711;A61K35/76;A61K48/00;A61P1/14;A61P1/16;A61P3/00;A61P3/06;A61P3/10;A61P5/00;A61P5/50;A61P7/00;A61P7/04;A61P25/00;A61P25/28;A61P43/00;C07K14/145;C12N5/02;C12N5/10;C12N7/00;C12N15/866;C12P21/04;C12R1/91;(IPC1-7):C12P21/04;C12P21/06;C12N13/00;A61K39/07;C07H21/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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