Receptor-binding determinant from leukaemia inhibitory factor

摘要

The present invention relates generally to molecules carrying one or more binding determinants for alpha-chain of human Leukaemia Inhibitory Factor binding receptor and to genetic sequences encoding same. More particularly, the present invention contemplates a molecule which is non-naturally occurring and which comprises a carrier portion and an active portion and wherein the active portion comprises amino acid residues or chemical equivalents thereof which constitute a binding determinant for the alpha chain of the human leukaemia inhibitory factor (hLIF) binding receptor.