MEDICINE FOR CENTRAL NERVOUS NEUROCLADISM CONTAINING DICTYOSTEROL AS ACTIVE INGREDIENT

摘要

PROBLEM TO BE SOLVED: To obtain the subject medicine having excellent neurocladism action on central nervous cells, especially aged central nervous cells and useful as a therapeutic agent including an antidemential agent for neurodegenerative diseases by including a compound derived from a specific cellular mucosa. SOLUTION: This medicine comprises dictyosterol of the formula as an active ingredient. The compound of the formula can be obtained by culturing a cellular mucosa, extracting the compound of the formula which is intracellularly present with an organic solvent after finishing the culture, isolating the compound of the formula in the extract from the crude product by using a usually known purification method and washing the isolated compound with an organic solvent. The compound of the formula is preferably produced by culturing the cellular mucosa for 7-10 days by agar plate culturing method. The culturing temperature is suitably 20-25 deg.C. A form and a pathway which are pharmaceutically hitherto well-known are applied for administration of the medicine and the medicine is preferably administered at a daily dose of 0.001-100 mg divided into one to several portions.