发明名称 N-hydroxyurea derivative and pharmaceutical composition containing the same
摘要 An N-hydroxyurea derivative having an antiallergic action or anti-inflammatory action having the formulawherein, either one of R1, R3, and R4 represents A, either one of the other groups of R1, R3, and R4 and R2 represents a 3-pyridyl group or 3-pyridylalkyl group, the remaining groups of R1, R2, R3, and R4 independently represent a hydrogen atom, halogen atom, or a substituted or unsubstituted C1 to C8 alkyl group, R5 represents a hydrogen atom or lower alkyl group, R6 represents a hydrogen atom, lower alkyl group, C3 to C7 cycloalkyl group, or a substituted or unsubstituted phenyl group, where the substituent represents a halogen atom, lower alkyl group, or lower alkoxy group, B represents a bond, C1 to C20 alkylene group, C2 to C8 alkenylene group, or C2 to C8 alkynylene group or B-C(R5) represents a C2 to C6 alkylene group having a benzene ring in the middle thereof or its pharmacologically acceptable salt or the hydrate or solvate thereof.
申请公布号 US6184238(B1) 申请公布日期 2001.02.06
申请号 US19990331624 申请日期 1999.06.23
申请人 NIKKEN CHEMICALS CO., LTD. 发明人 TAKANO MICHIKA;KOMATSU TOSHIYA;KAWAHARA YOSHIKAZU
分类号 C07D401/04;C07D401/06;(IPC1-7):A61K31/44 主分类号 C07D401/04
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