| 发明名称 |
C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
| 摘要 |
This invention is directed to novel (N-substituted) indole ICE/ced-3-inhibitor compounds. The invention is also directed to pharmaceutical compositions of such indole compounds, plus the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury.
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| 申请公布号 |
US6184244(B1) |
申请公布日期 |
2001.02.06 |
| 申请号 |
US19990345724 |
申请日期 |
1999.06.30 |
| 申请人 |
IDUN PHARMACEUTICALS, INC. |
发明人 |
KARANEWSKY DONALD S.;BAI XU |
| 分类号 |
C12N9/99;A61K31/40;A61K31/4025;A61K31/404;A61K31/405;A61K31/675;A61K38/00;A61K38/05;A61K38/06;A61K38/55;A61P1/04;A61P1/16;A61P1/18;A61P9/10;A61P13/12;A61P15/00;A61P19/00;A61P19/02;A61P25/00;A61P25/14;A61P25/28;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D209/12;C07D209/14;C07D209/30;C07K5/02;C07K5/023;C07K5/027;C07K5/04;(IPC1-7):A61K31/40;A61K31/402 |
主分类号 |
C12N9/99 |
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