CHROMATOGRAPHIC PROCESS FOR PURIFYING PLASMID DNA USING SUPERPOROUS SUPPORTS

摘要

The present invention relates to a process for purifying plasmid DNA. Specifically, the present invention is applied in the purification of plasmid DNA with chromatographic techniques, which use insoluble supports. Its main novelty lies in the fact that the supports used are considered superporous supports. The outcome of the chromatographic operations might be largely improved when such supports, say superporous, are used, leading to a significant increase of both the overall process productivity and yield.