The present invention is directed to tetrahydro-imidazopyridinyl compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
申请公布号
WO0107046(A1)
申请公布日期
2001.02.01
申请号
WO2000US19615
申请日期
2000.07.19
申请人
MERCK & CO., INC.;DINSMORE, CHRISTOPHER, J.;GRAHAM, SAMUEL, L.;WILLIAMS, THERESA, M.
发明人
DINSMORE, CHRISTOPHER, J.;GRAHAM, SAMUEL, L.;WILLIAMS, THERESA, M.
