5-(E)-BROMOVINYL URACIL ANALOGUES AND RELATED PYRIMIDINE NUCLEOSIDES AS ANTI-VIRAL AGENTS AND METHODS OF USE

摘要

The present invention relates to pyrimidine nucleoside compounds and their u se to treat viral infections of Varicella Zoster Virus, Epstein Barr Virus and Kaposi's Sarcoma virus, also known as HV-8 and related complications of thes e viral infections. In another aspect of the present invention, the use of one or more nucleoside compound to increase the retention or half-life of 5- fluorouracil (FU) in patients is also described.